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REVIEW ARTICLE
Year : 2010  |  Volume : 1  |  Issue : 1  |  Page : 5-8

Calcitonin gene-related peptide and menopause


1 Post-Graduate Department of Obstetrics and Gynecology, Government Medical College, Jammu, Jammu and Kashmir, India
2 Post-Graduate Department of General Medicine, Government Medical College, Jammu, Jammu and Kashmir, India
3 Post-Graduate Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India

Correspondence Address:
Sudhaa Sharma
Post-Graduate Department of Obstetrics and Gynecology, Government Medical College, Jammu 180 001, Jammu and Kashmir
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-7800.66985

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The review summarizes recent findings with respect to pathophysiological role of calcitonin gene-related peptide (CGRP), in postmenopausal symptoms and diseases, which has opened horizons in understanding pathophysiology of menopause in a better way. Current evidences strongly propose a need to develop CGRP receptor antagonists, which may prove beneficial in many prevalent menopausal symptom/diseases such as vasomotor symptoms, cardiovascular risk, obesity, and major depressive disorder, in which CGRP levels are elevated.


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