Journal of Mid-life Health Journal of Mid-life Health
Home | About us | Editorial board | Search | Ahead of print | Current Issue | Past Issues | Instructions | Online submission | Subscribe | Advertise Users Online: 512  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size 


REVIEW ARTICLE
Year : 2014  |  Volume : 5  |  Issue : 3  |  Page : 111-114

Bisphosphonate drug holidays: Can we recommend currently?


1 Department of Pharmacology, Government Medical College, Jammu and Kashmir, India
2 Department of Obstetrics and Gynaecology, Government Medical College, Jammu and Kashmir, India
3 Department of G Medicine, Government Medical College, Jammu and Kashmir, India

Correspondence Address:
Dr. Sudhaa Sharma
Department of Obstetrics and Gynaecology, Government Medical College, Jammu and Kashmir
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-7800.141186

Rights and Permissions

Bisphosphonates (BP) are the mainstay of treatment for osteoporosis. Subtrochanteric or diaphyseal fractures have been reported with long term use of BP, which raised world-wide debate on two aspects, i.e., for how long the BP is to be given and potential advantages/role of BP drug holidays. BP accumulates in bone with some persistent protective effect after therapy is stopped endorses the concept. Theoretically, a drug holiday may be a considerable option to decrease risks of BP, which continuing the protection from fractures but the level of evidence and data supporting the concept of drug holidays is a week. Hence, no specific recommendations are available on BP drug holidays from major available treatment guidelines on postmenopausal osteoporosis. Hence, before it is recommended it requires more robust research in this field.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3419    
    Printed134    
    Emailed1    
    PDF Downloaded598    
    Comments [Add]    
    Cited by others 2    

Recommend this journal