Journal of Mid-life Health Journal of Mid-life Health
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Year : 2015  |  Volume : 6  |  Issue : 3  |  Page : 132-133

Elderly female with Autoimmune hemolytic anemia

Department of Medicine, All India Institute of Medical Sciences, Bhubaneswar, Orissa, India

Correspondence Address:
Anupam Dey
Department of Medicine, All India Institute of Medical Sciences, Bhubaneswar - 751 019, Orissa
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-7800.165596

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Autoimmune hemolytic anemia (AIHA) is a rare disease with an estimated prevalence of around 17/100,000. It is often difficult to diagnose and treat AIHA, especially in elderly. A 60-year-old female was admitted with the complaints of low grade fever, on-off for 6 months, progressive fatigue and dyspnea on exertion. She was transfused with three units of blood within these 6 months. Examination revealed pallor, edema, hemic murmur, and palpable liver. Hb was 2.9 gm%, T Bil 5.2 mg/dl, ESR 160 mm, and reticulocyte count 44.05%. Direct Coombs test was positive, anti-nuclear antibody (ANA) and Anti ds DNA were positive. A diagnosis of systemic lupus erythematosus (SLE) with AIHA was considered and patient was transfused with two units of packed red cells and put on steroid (prednisolone) at 1 mg/kg body weight daily. After 3 weeks, her Hb had increased to 10.4 gm% with gross clinical improvement.

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